靶标信息
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
同义词
2610022J01Rik; Acetyl-Histone H2; AV127319; bA317E16.3; CG17949; CG17949 gene product from transcript CG17949-RA; CG17949-PA; CG33868; CG33868 gene product from transcript CG33868-RA; CG33868-PA; CG33870; CG33870 gene product from transcript CG33870-RA; CG33870-PA; CG33872; CG33872 gene product from transcript CG33872-RA; CG33872-PA; CG33874; CG33874 gene product from transcript CG33874-RA; CG33874-PA; CG33876; CG33876 gene product from transcript CG33876-RA; CG33876-PA; CG33878; CG33878 gene product from transcript CG33878-RA; CG33878-PA; CG33880; CG33880 gene product from transcript CG33880-RA; CG33880-PA; CG33882; CG33882 gene product from transcript CG33882-RA; CG33882-PA; CG33884; CG33884 gene product from transcript CG33884-RA; CG33884-PA; CG33886; CG33886 gene product from transcript CG33886-RA; CG33886-PA; CG33888; CG33888 gene product from transcript CG33888-RA; CG33888-PA; CG33890; CG33890 gene product from transcript CG33890-RA; CG33890-PA; CG33892; CG33892 gene product from transcript CG33892-RA; CG33892-PA; CG33894; CG33894 gene product from transcript CG33894-RA; CG33894-PA; CG33896; CG33896 gene product from transcript CG33896-RA; CG33896-PA; CG33898; CG33898 gene product from transcript CG33898-RA; CG33898-PA; CG33900; CG33900 gene product from transcript CG33900-RA; CG33900-PA; CG33902; CG33902 gene product from transcript CG33902-RA; CG33902-PA; CG33904; CG33904 gene product from transcript CG33904-RA; CG33904-PA; CG33906; CG33906 gene product from transcript CG33906-RA; CG33906-PA; CG33908; CG33908 gene product from transcript CG33908-RA; CG33908-PA; CG33910; CG33910 gene product from transcript CG33910-RA; CG33910-PA; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; Dmel\CG17949; Dmel\CG33868; Dmel\CG33870; Dmel\CG33872; Dmel\CG33874; Dmel\CG33876; Dmel\CG33878; Dmel\CG33880; Dmel\CG33882; Dmel\CG33884; Dmel\CG33886; Dmel\CG33888; Dmel\CG33890; Dmel\CG33892; Dmel\CG33894; Dmel\CG33896; Dmel\CG33898; Dmel\CG33900; Dmel\CG33902; Dmel\CG33904; Dmel\CG33906; Dmel\CG33908; Dmel\CG33910; Dmel_CG17949; Dmel_CG33868; Dmel_CG33870; Dmel_CG33872; Dmel_CG33874; Dmel_CG33876; Dmel_CG33878; Dmel_CG33880; Dmel_CG33882; Dmel_CG33884; Dmel_CG33886; Dmel_CG33888; Dmel_CG33890; Dmel_CG33892; Dmel_CG33894; Dmel_CG33896; Dmel_CG33898; Dmel_CG33900; Dmel_CG33902; Dmel_CG33904; Dmel_CG33906; Dmel_CG33908; Dmel_CG33910; fj05g08; GL105; H2B; H2B 291A; H2B 291B; H2b 613; H2B clustered histone 15; H2B clustered histone 19; H2B clustered histone 2, pseudogene; H2B clustered histone 21; H2B clustered histone 5; H2B clustered histone 8; H2B GL105 antibody; H2B histone family member M; H2B histone family member W testis-specific; H2B histone family member W, testis specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member M; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member S; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B histone family, member W, testis-specific; H2B K; H2B type 12; H2B.1; H2B.1 antibody; H2B.1A; H2B.1B; H2B.2; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/q; H2B/r; H2B/S; H2B1; H2B1.1; H2B1.2; H2b-143; H2B2; h2B-221; H2b-291b; H2b-613; H2Bb; H2BC10; H2BC15; H2BC19; H2BC21; H2BC2P; H2BC4; H2BC5; H2bc6; H2BC7; H2bc8; H2b-f; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFQ; H2BFR; H2bfs; H2BFT; H2BFU; H2BFWT; H2BGL105; H2BJ; H2b-j; H2BK; H2BK12ac; H2BK15ac; H2BK5ac; H2b-l; H2b-n; H2BQ; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRA-interacting protein 2; HIRIP1; HIRIP2; His2B; His2B:CG17949; His2B:CG17949-PA; His2B:CG33868; His2B:CG33868-PA